This is exactly the question I had asked here.chad said:Best bet is to run 1 per channel. Honestly a quad cable is not the best for a permanent install as the conductors in parallel will add to the capacitance of the cable. I prefer an install grade cable such as gepco 61801 (single pair) or 61802 (dual pair) or the belden equivalent. They have a drain conductor and a 100% foil shield. It's a damn good cable with low capacitance, especially at $.20 a foot RETAIL!