Given the option of a single 10" D4 or a pair of 8" D2 subs with the same 300W mono either way, why would you go one way or the other? The pair of 8s has about 30% more cone area and 2mm less Xmax but 4 coils running off that 300W. Image Dynamics ID are the specific subs in question. Would your answer change if we were talking about Alpine Type R?
EDIT - only considering sealed enclosure due to space.
EDIT - only considering sealed enclosure due to space.