reliable? I worry about any amp that runs mids/tweets on other channels while trying to push a sub off one power supply...its a lot of stress...
thats why I wonder if there is some difference in the JL...
darn it and i just bought a used one too! ! ! i was going to power a pair of ed 6500 and ed 6000v2's and a pair of ed7kv.2 subs. . .

any suggestions for a nooB? ? ? :blush:
Guys, multi-channel amps powering a full system is not a new thing, this has been done for years. The sole reason a company like JL Audio would offer a 6 channel amp in their lower line product is to offer an all-in-one solution to the consumer on a budget. The 6450 amps were designed as a single amp solution to power the most common system config, FRONT, REAR and SUB configs. The amp is rated as such:
6 x 45W @ 4 ohms (12.5V - <0.08% THD)
6 x 70W @ 4 ohms (14.5V - <1% THD)
6 x 75W @ 2 ohms (12.5V)
6 x 110W @ 2 ohms (14.5V)
3 x 150W @ 4 ohms bridged (12.5V)
3 x 220W @ 4 ohms bridged (14.5V)
Fuse: External 60A
So,
At 12.5 volts, the amp will produce 450 watts of total power
At, 14.4 volts the amp will produce 660 watts of total power
That is not a ton of power but it is enough to stress out a too small power supply running 6 channels. The solution is to use a power supply that can deliver, and that is what JL did and what many modern car audio amplifier designers do. The power supply is unregulated so you get more power with a higher input voltage. I remember this amp was tested by a mag and it did the rated power in all channels at 12.5 volts. So, feel free to run the amp with a sub on channels 5&6 that is what it was designed for and I am sure the amp will deliver the goods.I don't know anything about the reliability of the A and e series amps but not every amp is going to fail...and chances are if these amps were used they would have failed by now. At under $200 one really can't go wrong with these...however, running two amps is always what we try to do but space savings does not always allow us to do that.
As far as the Slash amps, I did a couple of systems for a friend and he had the 500/5 powering a Front,Rear, Sub system. The amp was actually in a storage compartment in a Ford Explorer for a couple of years and it never shut down or had any noise issues. He still has the amp and plan to put it in a third system running full.
I remember my old 5 channel MTX Thunder5400x (ten years ago) was good for over 800 watts at full tilt. That amp was only 15"x9"x2" and used to get as hot as a griddle but it used to thump a full system.