@rubbertoe i am only intimatly familiar with the RC, so take the following as more of a probably. There may be some IS/RC differences, and more again some with the sales region difference. That said, IS and RC have the same dash and headunit styling.
I also have the luxury, not a F sport, so you may also have noise cancelling or artificial exhaust sounds to contend with, i honestly can't recall all the features by model and model year, let alone sales region.
There are interfacing solutions available for non-nav units, also interfacing solutions for later model years with ML.
Non ML with navigation factory setup will likely be a digital MOST signal into the factory amp.
This signal will contain the audio information for music and phone calls, and likely also fader info, volume level, sound levelling, surround sound processing. Long story short, factory amp does more then just make the signal louder.
Because of this, to retain full factory functionality, the solution is to take the speaker outputs of the factory amp into the high level inputs of a DSP, do what you want to them, then send them on to your aftermarket amps and then your speakers.
So system would be Headunit > factory amp > DSP > aftermarket amp(s) > speakers.
You can have it setup like that and working factory like, and also feed directly into the DSP from your phone when you want, doesnt have to be one or the other. Just need a DSP remote control for the volume.
Would be
Phone > DSP > Amps > speakers
Could also consider something like the Helix BT streamer, these have the ability to handle phone calls aswell so completely eliminate the factory headunit and amp but still have phonecalls. Is especially attractive for when the expensive factory headunit or amp dies, which isnt uncommon.
DSP AMP just combines two stages into one physical unit, is more convenient for install and wiring, but with less flexibility regarding amplifier power/selection and system changes.
Regarding resale, you would simply remove your aftermarket system and plug the factory amp outputs back into the factory speaker wiring. There is ZERO need to permanently remove or alter any part of the factory setup.
To make this easy you want to get an amplifier T-Harness, several companies make them, model should be APH-TY02.
This gives you access to the amplifier outputs and factory speaker wiring without having to cut anything factory, simply plugs in.
Can utilize the factory speaker wiring without an issue, adapters for the factory speaker plugs are available, would just have to run another pair of speaker wires to your your tweeters for a 3 way.
Photos are my amplifier T-Harness and the speaker adapters, 32 is the doors, 45 is my dash corners.